Lentiviral Vector Production from a Stable Packaging Cell Line Using a Packed Bed Bioreactor
نویسندگان
چکیده
منابع مشابه
Scalable Lentiviral Vector Production Using Stable HEK293SF Producer Cell Lines
Lentiviral vectors (LV) represent a key tool for gene and cell therapy applications. The production of these vectors in sufficient quantities for clinical applications remains a hurdle, prompting the field toward developing suspension processes that are conducive to large-scale production. This study describes a LV production strategy using a stable inducible producer cell line. The HEK293 cell...
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ژورنال
عنوان ژورنال: Molecular Therapy - Methods & Clinical Development
سال: 2020
ISSN: 2329-0501
DOI: 10.1016/j.omtm.2020.08.010